C-REACTIVE PROTEIN LEVELS AND THE SEVERITY OF COVID-19

  • Mirza Waseem Javed Combined Military Hospital Kohat Pakistan
  • Muhammad Anwar Combined Military Hospital Kohat Pakistan
  • Tariq Mehmood Bangash Combined Military Hospital Kohat Pakistan
  • Rizwan Ul Haq Satti Combined Military Hospital Kohat Pakistan
  • Mehar Rehman Combined Military Hospital Kohat Pakistan
  • Uzair Ijaz Malik Combined Military Hospital Kohat Pakistan
Keywords: COVID-19, C-reactive protein, Disease severity classification

Abstract

Objective: To compare the C-reactive proteinlevels in different groups of COVID-19 patients to assess disease severity.

Study Design: Cross sectional study.

Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun2020.

Methodology: Forty fiveConfirmed cases of COVID-19 patients were included by non-probability consecutive sampling. Patients were divided into five groups (Asymptomatic, Mild, Moderate, Severe and Critical). Serum sample for C -reactiveprotein levels were collected at presentation and compared in different clinical groups by Paired sample “t” test andoneway Anova(Post Hoc LSD).

Result: Out of 45 cases in our study28 (62.2%) were male and 17 (37.8%) were female. Mean age of patients was 51.96 ± 16 and mean C-reactiveproteinlevels were 76.61± 75 mg/L. When compared by paired sample t-test C-reactive proteinlevels were: higherin the mild patient group than asymptomatic group, higher inthe moderate groupthan mild group, higherin severe group than moderate group and those in the critical group were higherthan those in the severe group. The difference was statistically significant with p-value <0.05 in each group.

Conclusion: C-reactive proteinlevelswerelowest in asymptomatic and highest in critical patients inearly COVID-19. This may help guide management.

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Published
2020-09-14
How to Cite
Javed, M., Anwar, M., Bangash, T., Satti, R., Rehman, M., & Malik, U. (2020). C-REACTIVE PROTEIN LEVELS AND THE SEVERITY OF COVID-19. Pakistan Armed Forces Medical Journal (PAFMJ), 70(2), S603-07. Retrieved from https://mail.pafmj.org/index.php/PAFMJ/article/view/5320
Section
Original Articles