COMPARISON OF FIRST MORNING VOID URINE SPECIMEN FOR ALBUMIN TO CREATININE RATIO COMPARING WITH 24-HOUR URINARY ALBUMIN EXCRETION IN DETECTING MICROALBUMINURIA IN TYPE 2 DIABETICS

Albumin To Creatinine Ratio of Urine in Type 2 Diabetics

  • Fawad Ahmad Military Hospital Rawalpindi Pakistan
  • Aamir Hussain 63- Medical Battalion Multan Pakistan
  • Omer Bin Abdul Aziz 5- Mountain Medical Battalion Forward Kahuta AJK Pakistan
  • Naveed Ahmed Military Hospital Rawalpindi Pakistan
Keywords: Albumin to Creatinine Ratio, Diabetes Mellitus, Microalbuminuria, 24 Hour Urinary Albumin

Abstract

Objectives: To determine the accuracy of first morning void urine specimen for Albumin to Creatinine Ratio (ACR) comparing with 24-hour urinary albumin excretion in detecting microalbuminuria in type 2 diabetics. Study Design: Cross Sectional study Place and Duration of Study: Military Hospital Rawalpindi, from Apr 2013 to Oct 2013. Patients and Methods: One hundred & twenty patients with type 2 Diabetes Mellitus (DM) fulfilling the inclusion criteria were included in study using consecutive non-probability sampling. A standard protocol was followed for specimen collection. Urine collection was started from the next day of admission. Results: Mean random plasma glucose level was 174.54 ± 33.06 mg/dL, mean HbA1c was 8.5 ± 1.32 %, mean urinary albumin 130.26 ± 47.25 mg/24 hour and mean ACR was 104.30 ± 51.56 mg/g. Area under ROC curve was 0.964 for microalbuminuria by ACR. Spearman’s rank-order coefficient (rs) was 0.696 for ACR and 24 hour albumin excretion. Conclusion: ACR in first morning void urine accurately detected early microalbuminuria in type 2 diabetics.

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Published
2016-04-30
How to Cite
Ahmad, F., Hussain, A., Aziz, O., & Ahmed, N. (2016). COMPARISON OF FIRST MORNING VOID URINE SPECIMEN FOR ALBUMIN TO CREATININE RATIO COMPARING WITH 24-HOUR URINARY ALBUMIN EXCRETION IN DETECTING MICROALBUMINURIA IN TYPE 2 DIABETICS. Pakistan Armed Forces Medical Journal, 66(2), 240-43. Retrieved from https://mail.pafmj.org/index.php/PAFMJ/article/view/505
Section
Original Articles