ANTIBIOTIC THERAPY VERSUS APPENDICECTOMY IN UNCOMPLICATED ACUTE APPENDICITIS IN TERMS OF EFFICACY

Antibiotic Therapy Versus Appendicectomy

  • Mudassar Abbas Zaidi 5 Mountain Medical Battalion Forward Kahuta Pakistan
  • Tashfeen Bin Nazeer 5 Mountain Medical Battalion Forward Kahuta Pakistan
  • Omer Bin Abdul Aziz 5 Mountain Medical Battalion Forward Kahuta Pakistan
  • Naveed Ahmed 5 Mountain Medical Battalion Forward Kahuta Pakistan*Combined Military Hospital Skardu/National University of Medical Sciences (NUMS) Pakistan
  • Tahir Asad 5 Mountain Medical Battalion Forward Kahuta Pakistan
  • Zaigham Salim Dar 64 Medical Battalion Peshawar Pakistan
Keywords: Acute Appendicitis, Antibiotic therapy, Appendectomy, Efficacy

Abstract

Objective: To compare antibiotic therapy and appendectomy in uncomplicated acute appendicitis in terms of
efficacy.
Study Design: Randomized controlled trial.
Place and Duration of Study: Surgical Ward Forward Treatment Centre (FTC), 5 Mountain Medical Battalion
Forward Kahuta Azad Jammu Kashmir (AJK), from Oct 2011 to Mar 2013.
Material and Methods: A total of 103 patients with clinical diagnosis of acute appendicitis (AA) were admitted
during the duration of study and divided into two groups by consecutive sampling. The antibiotic group
consisted of 51 patients who received intravenous antibiotics for 48 hours and oral antibiotics for another 8 days.
The appendectomy group comprised of 52 patients who all underwent standard appendectomy. All the patients
were followed up at 1 month and 1 year for assessing efficacy and post treatment complications.
Results: The efficacy of antibiotic treatment is 90.625% as compared to appendectomy which was 88.46%
(p=0.759) at 1 month follow up after treatment. At one year post treatment, the comparison between the efficacy
of antibiotic therapy (71.87%) and appendectomy (87.14%) remains statistically insignificant (p=0.055).
Conclusion: Antibiotic therapy is comparable to appendectomy in AA in terms of efficacy at 1 month and 1 year
post treatment.
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Published
2018-10-29
How to Cite
Zaidi, M. A., Bin Nazeer, T., Abdul Aziz, O. B., Ahmed, N., Asad, T., & Salim Dar, Z. (2018). ANTIBIOTIC THERAPY VERSUS APPENDICECTOMY IN UNCOMPLICATED ACUTE APPENDICITIS IN TERMS OF EFFICACY. Pakistan Armed Forces Medical Journal, 67(1), 98-101. Retrieved from https://mail.pafmj.org/index.php/PAFMJ/article/view/165
Section
Original Articles