ISOLATION OF MICROFLORA INVOLVED IN CHRONIC SUPPURATIVE OTITIS MEDIA AND FINDING ANTIBIOTIC SENSITIVITY IN KHARIAN
Microflora of Chronic Suppurative Otitis Media
Keywords:Antibiotic sensitivity, Chronic suppurative otitis media, Methicillin resistant Staphylococcus aureus (MRSA)
Objective: The objective of the study is to find out the microorganisms implicated in chronic suppurative otitis media (CSOM) and to know the sensitivity pattern of these microorganisms to commonly used antibiotics in Kharian.
Study Design: Cross-sectional descriptive study.
Place and Duration of Study: The study was conducted in Combined Military Hospital (CMH) Kharian from January 2013 to Dec 2013.
Patients and Methods: One hundred and twenty (120) cases of clinically diagnosed CSOM were included in this study. Ear swabs were taken using commercially available sterile swab sticks and the samples were sent to the pathology lab under strict aseptic conditions to culture the microorganisms and find sensitivity pattern.
Results: Out of 120 cases included in the study, there were 56 (47%) females and 64 (53%) males with slight male dominance. The patients’ age range was from 2 years to 63 years. Highest frequency was of. Pseudomonas aeruginosa found in 51 (42.5%) cases followed by Staphylococcus aureus in 28 (23.4 %) cases, MRSA (Methicillin Resistant Staphylococcus aureus) in 7(5.8%) cases, Proteus in 6 (9.2%) cases, Klebsiella in 8 (6.7%) cases and E-Coli in 6 (5%) case. Pseudomonas aeruginasa was highly sensitive to Ciprofloxacin, Amikacin and Sulbactum-cefoperazone. Staphylococcus aureus had high sensitivity to Amoxi-clav, Amikacin etc. MRSA (Methicillin Resistant Staphylococcus aureus) was 100% sensitive to Vancomycin.
Conclusion: Pseudomonas aeruginosa and Staphylococci are the commonest organisms involved in CSOM and they show good sensitivity to the fluoroquinolones and aminoglycosides which are available in local preparations. The knowledge of microbiological flora and its sensitivity to commonly used antibiotics is important for rationale use of the antibiotics and to avoid development of resistance.